A hybrid AI model combining clinical and mammographic data outperformed single-source models in predicting 2-year breast cancer risk, showing robustness across breast density and cancer type.
Why It Matters To Your Practice
▪ Improved risk stratification may enable more tailored screening recommendations.
▪ Earlier identification of high-risk patients could enhance surveillance and outcomes.
▪ Consistent performance across breast densities supports broader applicability.
▪ Integrating AI tools may streamline workflow and risk assessment.
Clinical Implications
▪ Hybrid AI models deliver higher accuracy than image- or clinical data-only approaches.
▪ Best results seen for screen-detected cancers; performance was lower for interval cancers.
▪ Supports individualized screening intervals and supplemental imaging decisions.
▪ Potential to optimize resource allocation within screening programs.
Insights
▪ Combining clinical and imaging features leverages complementary strengths.
▪ Robustness across breast density quartiles addresses a common limitation.
▪ Machine learning methods like ERT and CNN can be synergistic.
▪ Real-world validation is needed before clinical integration.
The Bottom Line
▪ AI models integrating clinical and mammographic data improve short-term breast cancer risk prediction, supporting personalized, data-driven screening strategies.